Which Wiiscrubber version are you using? I recommend 1.21...
About that io_read, that's usually from a corrupted iso (maybe from when you were injecting the .thp) Which Brawl disc your are using 4gb or the 8gb one?
im using 1.4, but i'll give it a try with 1.21 if something changes. about which disc is the 8gbs one D:.
are you doing this for dolphin, or playing it on teh wii?
Wii D:
edit: damnit, i cant find the 1.21, can you upload it please? :3